Brothers by Different Mothers
For the 1956 production of The Ten Commandments, "Charlton Heston was chosen for the role of Moses by Cecil B. DeMille because he bore a resemblance to Michelangelo's statue of Moses in Rome" (Source). I find this interesting because Heston played the immortal artist in The Agony and the Ecstasy (1965).
What do you think? Mickey and Chuck's similarity is pretty spot on if you ask me and the comparison to the Moses statue comes off rather well, too. I think it's the nose.